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Pro-drug Technology: Additive Manufacturing of Personalised Drug Dosage Forms
Innovative 3D printable prodrugs are used to create solid dosage forms using additive manufacturing (AM) technology. Active ingredients, such as ibuprofen/paracetamol, loaded tablets would contain one or more structures and cavities (or similar) to provide a tailorable drug release profile and enable customisable delay/transit through the stomach/GI...
Published: 29/06/2022   |   Inventor(s): Ricky Wildman, Yinfeng He, Giuseppe Mantovani, Derek Irvine, Clive Roberts, Richard Hague, Christopher Tuck, Vincenzo Taresco
Category(s): Healthcare
Thapsigargin II and Thapsigargin III derivatives for enhancing immune response to viral infection
Influenza/RSV immunomodulation therapyHost-centric response reduces resistanceIn brief:Small molecule stimulates a highly effective host antiviral response against influenza virus and respiratory syncytial virus (RSV) which includes:Interference of viral protein transport and assembly, and enhanced type I and III interferon response.Compound can be...
Published: 28/05/2020   |   Inventor(s): Kin-Chow Chang
Category(s): Healthcare
Regenerating Bone Tissue Using Resorbable Porous Microspheres
Porous Glass Microspheres A tailored, single-stage and scalable manufacturing process In brief Porous glass microspheres (MS) are produced via a novel flame spheroidisation process, enabling precise tailoring of MS porosity, size, chemistry and other variables to address a wide range of potential applications. Compared to other manufacturing techniques,...
Published: 08/04/2016   |   Inventor(s): Ifty Ahmed
Category(s): Biomedical, Engineering, Healthcare
Novel polymers which resist bacterial attachment
Antimicrobial Urinary Catheter The Opportunity ·We have developed a novel polymer which prevents bacterial adhesion. ·We are using it to coat urinary catheters to prevent encrustation and catheter associated urinary tract infection (CAUTI). ·We have shown that not only is the coating non-toxic and non-irritant, but that in vivo its use dramatically...
Published: 09/02/2012   |   Inventor(s): Morgan Alexander, Martyn Davies, Paul Williams, Jing Yang, Andrew Hook, Chien-Yi Chang, Robert Langer Jr., Daniel Anderson
Category(s): Biomedical, Healthcare, Pharmaceutical
Raman spectral imaging for automated Mohs Micrographic surgery of Basal Cell Carcinoma
Automated Detection and Imaging of Tumours During Surgery Summary Automated imaging and objective diagnosis of excised tissue specimens during cancer surgery would lead to increasing the efficacy of the most advanced surgical procedure. We have developed a model which enables Raman Micro-Spectroscopy (RMS) to be used as an alternative to histopathology...
Published: 23/11/2009   |   Inventor(s): Ioan Notingher, Hywel Williams, William Perkins, Sandeep Varma
Category(s): Healthcare
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