http://uon.technologypublisher.comBe the first to know about the latest inventions and technologies available from The University of Nottinghamen-USThu, 29 Jul 2010 13:14:25 GMTThu, 11 Feb 2010 08:46:29 GMThttp://blogs.law.harvard.edu/tech/rsslenas@inteum.comCopyright 2010, http://uon.technologypublisher.com/technology/4613Measuring material microstructure Summary An exciting new ultrasonic technique known as Spatially Resolved Acoustic Spectroscopy (SRAS) has been developed at the University of Nottingham. This technique, which can replaced EBSD, can direct image the microstructure of materials – for example titanium, steel and aluminium and be used to measure properties such as the grain orientation, grain size distribution and texture. It can also be used to measure and image coating thickness. The ability to map the material microstructure – in effect to image the grains – quickly and in a non-dest...Thu, 11 Feb 2010 08:46:29 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4613http://uon.technologypublisher.com/technology/4612Full field flow and vibration imagingReal-time, fast frame rate imaging of flow or vibration using the laser Doppler technique Summary Current cameras for flow and vibration imaging are limited in their ability to measure in real-time, and to measure dynamic events and fast rates of flow or vibration. They are based on scanning technologies which are slow and can take several minutes to acquire an image. Researchers at the University of Nottingham have developed a novel camera designed for full field flow and vibration imaging using the laser Doppler technique. By using a configuratio...Thu, 11 Feb 2010 08:14:06 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4612http://uon.technologypublisher.com/technology/4611Thu, 11 Feb 2010 07:37:41 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4611http://uon.technologypublisher.com/technology/4568Wed, 10 Feb 2010 01:35:38 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4568http://uon.technologypublisher.com/technology/4222Synthetic substrates for supporting pluripotent human embryonic stem cells Summary Current human embryonic stem cell (hESC) culture methods utilise either fibroblast feeder cells or Matrigel as a biological matrix to support pluripotency. We have developed a synthetic polymer substrate which provides an alternative to biological matrices that supports pluripotent hESCs to the same extent. Polystyrene thin films and commercially available tissue culture polystyrene (TCPS) can be processed using a surface treatment method. The resulting substrate has been shown to support the culture of ...Tue, 08 Dec 2009 08:38:50 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4222http://uon.technologypublisher.com/technology/4221Insulin-templating Nanoparticles Summary Nanotechnology is an area of increasing interest and, within the medical arena, has many potential uses. Significant research is being undertaken around the use of nanotechnology in the development of therapeutics, drug delivery, diagnostics and imaging. One factor to overcome is the biocompatibility of nanoparticles and a number to technologies have been developed around coating techniques. Academics within the University of Nottingham have developed a method which uses insulin, a recognised biocompatible material, as a template for nanoparticl...Tue, 08 Dec 2009 03:38:06 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4221http://uon.technologypublisher.com/technology/4209Ganoderma Lucidum Extract for use in Prostate Cancer Prevention Summary Ganoderma Lucidum (GL), also known as LingZhi in Chinese and Reishi in Japanese, is a popular medicinal fungus that was described 2000 years ago and is used to treat various diseases such as hypertension, diabetes, hepatitis, cancer and cardiovascular problems. GL has been demonstrated to possess anti-cancer activity. Many chemical constituents of GL have been identified. The polysaccharide and triterpene fractions of GL are believed to contribute the most to its anti-cancer effect, through, as yet, an unknown mech...Fri, 04 Dec 2009 09:14:05 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4209http://uon.technologypublisher.com/technology/4208Fri, 04 Dec 2009 08:17:26 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4208http://uon.technologypublisher.com/technology/4197Bacterial Cheat Technology Summary Antibiotic resistant bacteria are becoming an increasing issue across the healthcare arena. Whilst there are a number of different approaches being taken from researchers across the world to tackle this resistance, research at Nottingham University in collaboration with Texas Tech and Edinburgh Universities have identified a novel approach. The technology relates to modified bacterial cells that are defective in gene expression. Thus far the technology has been demonstrated to decrease the virulence of Pseudomonas aeruginosa in both an acute burn and...Mon, 23 Nov 2009 09:15:58 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4197http://uon.technologypublisher.com/technology/4196Mon, 23 Nov 2009 07:57:07 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4196http://uon.technologypublisher.com/technology/4195Fri, 20 Nov 2009 08:57:20 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4195http://uon.technologypublisher.com/technology/4194Platelet Aggregation Kit Summary The method enables blood samples to be fixed immediately after being taken from the patient and subsequently stored for up to 9 days at room temperature before platelet aggregation is determined using flow cytometry. Aggregation of blood platelets is central to thrombus formation which can lead to heart attacks, stroke or peripheral vascular disease. Monitoring platelet aggregation is therefore fundamental to the assessment of platelet function. A significant amount of validation of this method has been carried out by the development group in addition t...Fri, 20 Nov 2009 08:15:53 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4194http://uon.technologypublisher.com/technology/4192Fri, 20 Nov 2009 07:48:51 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4192http://uon.technologypublisher.com/technology/4191Target for Delaying Premature Labour Summary Pre-term delivery can result in a number of both short and long-term disabilities for the baby. Side effects of currently available drugs mean premature labour can only be delayed for up to 48 hours. This enables appropriate treatment to be provided to the mother in order to speed up the growth of vital organs within the baby. Being able to delay pre-term labour for a longer period of time would significantly increase survival rate of the babies, reduce the incidence of health complications for the child and lessen the economical impact on t...Fri, 20 Nov 2009 07:04:45 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4191http://uon.technologypublisher.com/technology/4190Potential Vaccine Candidate for Gonorrhoea Summary Neisseria gonorrhoeae causes the important sexually-transmitted infection Gonorrhoea. Researchers at University of Nottingham have identified novel vaccine candidate and therapeutic target for the prevention and treatment of infections caused by N. gohorrhoeae. Technical Information So called ‘house-keeping’ enzymes are ubiquitous in all cells and perform key roles in essential metabolic pathways. The old idea that one protein can only perform one function has now been dramatically changed with the concept of ‘moonlighting proteins’, w...Fri, 20 Nov 2009 06:00:46 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4190http://uon.technologypublisher.com/technology/4188Fri, 20 Nov 2009 04:18:10 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4188http://uon.technologypublisher.com/technology/4187Platelet Stability Kit Summary The Platelet Stability Kit enables blood samples to be fixed immediately after being taken from the patient and subsequently stored for up to 6 days at room temperature before platelet activation is assessed via P-selectin measurements. These measurements are of extreme interest in order to diagnose cardiovascular disease and to monitor the effectiveness of anti-thrombotic drug therapies. A significant amount of validation of this method has been carried out by the development group in addition to the procedure being used for two multi-centre clinical tr...Fri, 20 Nov 2009 03:25:08 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4187http://uon.technologypublisher.com/technology/4183Swirl Induction in Pipes TechnologyBy inducing swirl in the flow through pipes it is possible to reduce wear and tear in piping systems used for the conveyance of particle-laden liquids or gases. This is done through an optimised geometry to induce swirl, which improves particle distribution. Professor N.J.Miles has invented a method which results in gradual induction of swirl, reducing wear and frequency of blockages but without significantly increasing turbulence in the system, so reducing pressure drop and pumping costs. ApplicationsProcesses involving the carriage of particle-laden...Thu, 19 Nov 2009 08:04:35 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4183http://uon.technologypublisher.com/technology/4182Surgical Membranes Summary Human amniotic membranes (AMs) are used as surgical material for numerous indications, including burns, wounds and surgery for the abdomen, head, pelvic region and ocular surface. One limitation of the use of AM in surgery is the large inter-donor variation and the inconsistencies in the current methods of preparation, preservation and processing of the membrane. This leads to variation in the clinical efficacy of the procedures and the degree of scarring that occurs following surgery.AM are also extensively used in tissue-engineering as a substrate upon whi...Thu, 19 Nov 2009 07:49:58 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4182http://uon.technologypublisher.com/technology/4181Novel stereoselective catalyst for the polymerisation of carbonyl containing or cyclic monomers TechnologyBiodegradable, biocompatible and bioresorbable polymers/plastics, such as polylactide (PLA), are finding an increasing number of applications in the biomedical, food packaging and agricultural industries. These polymers may also be of interest to the engineering industry as an alternative to hydrocarbon polymers. Dr Polly Arnold in the School of Chemistry at the University of Nottingham has developed a novel stereoselective non-toxic catalyst that can be used to generate high-mel...Thu, 19 Nov 2009 07:25:21 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/4181http://uon.technologypublisher.com/technology/3590Thu, 12 Nov 2009 04:44:10 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/3590http://uon.technologypublisher.com/technology/3589Genetic manipulation of Clostridium SummaryA research team led by Prof Nigel Minton has developed ways to engineer species of Clostridium to either introduce news genes into their chromosome or to delete gene sequences from their genome. The Clostridia have until now been recalcitrant species for gene manipulation, however, our new technology enables Clostridia to be manipulated for industrial, research and other applied uses. We have three current patent applications to protect various aspects of the technology. By way of example one is outlined here. This technology enables the seque...Thu, 12 Nov 2009 01:13:20 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/3589http://uon.technologypublisher.com/technology/3408Mon, 07 Sep 2009 09:37:43 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/3408http://uon.technologypublisher.com/technology/3347Fri, 21 Aug 2009 09:40:52 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/3347http://uon.technologypublisher.com/technology/3346Fri, 21 Aug 2009 09:09:24 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/3346http://uon.technologypublisher.com/technology/2624Wed, 27 May 2009 08:37:36 GMTlenas@inteum.comhttp://uon.technologypublisher.com/technology/2624